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International Journal of Nursing Research. 2020; 2: (3) 1; DOI: 10.12208/j.ijnr.20200067.

Early parenteral nutrition combined with enteral nutrition in postoperative patients with liver cancer
早期肠外营养联合肠内营养在肝癌术后患者营养支持中的应用研究

作者: 黄珍凤*,马娜,卜冬梅,陶静,龚连生

中南大学湘雅医院

*通讯作者:黄珍凤,单位:中南大学湘雅医院;

引用本文: 黄珍凤,马娜,卜冬梅,陶静,龚连生. 早期肠外营养联合肠内营养在肝癌术后患者营养支持中的应用研究[J]. 国际护理学研究, 2020, 2(3) : 229-232.
Published: 2020-05-19

摘要

目的 研究早期肠外营养(PN)联合肠内营养(EN)在肝癌术后患者营养支持中的应用价值。方法:将我院收治的76例肝癌术后患者随机分为研究组(n=38)和对照组(n=38),对照组患者行单纯EN营养支持,研究组患者行早期PN联合EN的营养支持方案。于2组患者营养支持干预前后,检测营养指标[血清前白蛋白(PA)和白蛋白(ALB)]和免疫功能指标[CD3+、CD4+、CD8+、CD4+/ CD8+],同时,观察并统计2组患者的住院时间及卧床时间。结果:营养支持干预后,研究组PA、ALB均高于对照组(P<0.05),CD3+、CD4+、CD4+/ CD8+均高于对照组(P<0.05)。在平均住院时间、卧床时间上,研究组均短于对照组(P<0.05)。结论:于肝癌术后患者营养支持中应用早期PN联合EN可有效提高患者的营养水平和免疫功能,加快康复进程。

关键词: 肝癌;术后营养支持;肠外营养;肠内营养;免疫功能

Abstract

Objective To study the value of early parenteral nutrition (PN) combined with enteral nutrition (EN) in nutritional support of patients with liver cancer after operation.
Methods 76 patients with liver cancer were randomly divided into two groups: the study group (n = 38) and the control group (n = 38). The patients in the control group received simple en nutrition support, and the patients in the study group received early PN combined with en nutrition support. Before and after nutritional support intervention, nutritional indexes (PA and ALB) and immune function indexes (CD3+, CD4+, CD8+, CD4+ / CD8+) were measured. Meanwhile, the length of stay and bed time were observed and counted.
Results after the intervention of nutritional support, PA and ALB in the study group were higher than those in the control group (P < 0.05), CD3 +, CD4 +, CD4 + / CD8 + were higher than those in the control group (P < 0.05). The average length of stay in hospital and bed time in the study group were shorter than those in the control group (P < 0.05).
Conclusion   early PN combined with en can effectively improve the nutritional level and immune function of patients with liver cancer, and accelerate the rehabilitation process.

Key words: liver cancer; postoperative nutritional support; parenteral nutrition; enteral nutrition; immune function

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