摘要
目的 分析术中冷冻病理切片在乳头状甲状腺癌诊断中的价值。方法 选择2023年9月至2024年9月某院收治的110例疑似乳头状甲状腺癌患者为研究样本,所有疑似患者均采取术中冷冻病理切片检查及术后术后石蜡切片检查,将术后术后石蜡切片检查结果作为金标准,比较两种检查方式的诊断效能及不同类型乳头状甲状腺癌的诊断符合率。结果 术中冷冻病理切片检查的诊断的敏感度、特异度以及准确度分别为97.98%、72.73%、95.45%;术中冷冻病理切片检查与术后石蜡切片检查诊断出不同类型乳头状甲状腺癌的诊断结果呈近似水平(P>0.05)。结论 术中冷冻病理切片是一种快速、有效的诊断手段,能够为乳头状甲状腺癌的及时手术治疗提供可靠的病理依据。
关键词: 乳头状甲状腺癌;术中冷冻病理切片;石蜡切片;诊断效能;类型
Abstract
Objective To analyze the value of intraoperative frozen pathological sections in the diagnosis of papillary thyroid carcinoma. Methods 110 suspected papillary thyroid cancer patients admitted to our hospital from September 2023 to September 2024 were selected as the research sample. All suspected patients underwent intraoperative frozen pathological section examination and postoperative paraffin section examination. The results of postoperative paraffin section examination were used as the gold standard to compare the diagnostic efficacy of the two examination methods and the diagnostic accuracy of different types of papillary thyroid cancer. Results The sensitivity, specificity, and accuracy of intraoperative frozen pathological section examination were 97.98%, 72.73%, and 95.45%, respectively; The diagnostic results of different types of papillary thyroid cancer diagnosed by intraoperative frozen pathological section examination and postoperative paraffin section examination are similar (P>0.05). Conclusion Intraoperative frozen pathological section examination is a fast and effective diagnostic method, which can provide reliable pathological basis for timely surgical treatment of papillary thyroid cancer.
Key words: Papillary thyroid cancer; Intraoperative frozen pathological sections; Paraffin section; Diagnostic efficacy; type
参考文献 References
[1] 严丹丹,饶洁,尹修恒,等. 基于深度迁移学习的甲状腺癌术中冷冻切片病理诊断模型研究[J]. 临床与实验病理学杂志, 2023,39(12):1448-1452.
[2] 李军,许研,卓倩. 甲状腺微小乳头状癌的术中冰冻病理诊断探讨[J]. 系统医学,2024,9(10):46-48.
[3] 李秀萍,陈燕. 甲状腺癌颈部淋巴结冷冻切片与术后病理不符原因分析[J]. 诊断病理学杂志,2024,31(8):715-718, 745.
[4] 王亚军,康骅,赵菁,等. 术中冷冻病理检查评估甲状腺乳头状癌淋巴结受累的价值[J]. 肿瘤研究与临床,2022, 34(2):92-96.
[5] 王瑾,昂琳,黄金,等. 9例散发性甲状腺髓样癌临床病理特征分析[J]. 中国现代普通外科进展,2021,24(6):455-459.
[6] 卢洪胜,叶民,曹学全,等. 基于颜色矩的病理判读算法在甲状腺癌冷冻切片病理辅助诊断中的探索[J]. 中华病理学杂志,2021,50(4):349-352.
[7] 孙金波. 甲状腺手术中快速冷冻病理切片的临床意义[J]. 中国医药指南,2020,18(17):74-75.
[8] 朱皓皞,温剑峰,任光玉,等. 冷冻切片联合细胞印片在甲状腺疾病术中快速病理诊断中的应用价值[J]. 诊断病理学杂志,2023,30(6):525-528,536.