摘要
目的 探讨持续血液滤过联合血浆置换治疗高血脂性急性胰腺炎的临床效果及总结有效的护理措施。方法 选择本院2024年06月-2025年6月收治的30例高脂血症性急性重症胰腺炎患者，分别给予对照组（15例）常规治疗和护理干预，给予观察组（15例）血浆置换联合持续血液滤过治疗联合综合护理。结果 患者炎症因子指标显示：均为观察组患者低于对照组，组间数据差异（P＜0.05）。同时，患者的禁食与禁水时间缩短，有效率明显提高，观察组护理效果更好（P＜0.05）。结论 高脂血症性急性重症胰腺炎患者的血脂水平较高，将血浆置换联合持续血液滤过作为治疗手段，辅以综合护理措施可以降低患者的血脂水平，促进血尿淀粉酶恢复。
关键词： 高脂血症性急性重症胰腺炎；血浆置换；血液滤过；甘油三酯；临床效果
Abstract
Objective To evaluate the clinical efficacy of continuous hemofiltration combined with plasma exchange in treating hyperlipidemic acute pancreatitis and to summarize effective nursing measures. Methods A total of 30 patients with hyperlipidemic acute severe pancreatitis admitted to our hospital between June 2024 and June 2025 were selected. The control group (15 cases) received conventional treatment with nursing intervention, while the observation group (15 cases) received plasma exchange combined with continuous hemofiltration along with comprehensive nursing care. Results Inflammatory factor indicators showed that all patients in the observation group had lower levels than those in the control group, with significant inter-group differences (P <0.05). Additionally, the fasting and fluid restriction periods were shortened, and the effectiveness rate was significantly improved in the observation group (P <0.05). Conclusion Hyperlipidemic acute severe pancreatitis patients exhibit elevated blood lipid levels. The combination of plasma exchange with continuous hemofiltration, supplemented by comprehensive nursing measures, can effectively reduce blood lipid levels and promote the recovery of serum amylase.
Key words： Hyperlipidemic acute severe pancreatitis; Plasma exchange; Hemofiltration; Triglycerides; Clinical efficacy
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