Research on multi enzyme cleaning solutions in the nursing of disinfection supply centers
多酶清洗液在消毒供应中心护理中的研究

摘要

目的 探讨不同类型多酶清洗液在消毒供应中心（CSSD）各类医疗器械清洗中的应用效果。方法 选取2024年6月至2025年3月医院CSSD回收的复用医疗器械1200件，按清洗方式与器械类型分为4组：A组（手工清洗+手工专用强效多酶清洗液）、B组（机械清洗+酶系清洗剂）、C组（超声清洗+全效型多酶清洗剂）、D组（传统清洗液对照组）。采用目测法、放大镜检查法、ATP生物荧光法及蛋白残留检测法评估清洗效果，记录器械腐蚀发生率、功能维持率。结果 A、B、C三组综合清洗合格率高于D组，器械腐蚀/老化发生率低于D组，功能维持率高于D组（P＜0.05）。结论 多酶清洗液通过复合酶协同作用可高效分解有机污染物，不同类型产品适配不同清洗场景，能显著提升器械清洗质量，降低腐蚀风险，值得在CSSD推广。

Abstract

Objective To explore the application effects of different types of multi enzyme cleaning solutions in the cleaning of various medical devices in disinfection supply centers (CSSD).
Methods 1200 reusable medical devices collected by CSSD in hospitals from June 2024 to March 2025 were selected and divided into four groups based on cleaning methods and device types: Group A (manual cleaning+manual specialized powerful multi enzyme cleaning solution), Group B (mechanical cleaning+enzyme based cleaning solution), Group C (ultrasonic cleaning+full effect multi enzyme cleaning solution), and Group D (traditional cleaning solution control group). Evaluate the cleaning effect using visual inspection, magnifying glass examination, ATP bioluminescence method, and protein residue detection method, and record the incidence of instrument corrosion and functional maintenance rate.
Results The comprehensive cleaning qualification rate of groups A, B, and C was higher than that of group D, the incidence of instrument corrosion/aging was lower than that of group D, and the functional maintenance rate was higher than that of group D (P<0.05).
Conclusion   Multi enzyme cleaning solution can efficiently decompose organic pollutants through the synergistic action of composite enzymes. Different types of products are suitable for different cleaning scenarios, which can significantly improve the quality of instrument cleaning and reduce corrosion risks. It is worth promoting in CSSD.