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Open Access Article

International Journal of Nursing Research. 2026; 8: (4) ; 31-34 ; DOI: 10.12208/j.ijnr.20260178.

Development of standardized nursing pathways and analysis of wound healing quality
NPWT联合PRP治疗的标准化护理方案在创面愈合中的应用与效果评价

作者: 庞珏, 黄倩倩 *, 唐欣, 鄢春宁

广西壮族自治区南宁市第一人民医院 广西南宁

*通讯作者: 黄倩倩,单位:广西壮族自治区南宁市第一人民医院 广西南宁 ;

发布时间: 2026-04-09 总浏览量: 117

摘要

目的 制定一套适用于3-4期压力性损伤NPWT联合PRP的规范化的护理方案,并且通过该方案的应用效果,评价NPWT联合PRP治疗3-4期压力性损伤创面愈合质量的效果。确定该方案是否可以运用到临床护理中。方法 将2024年1~12月份在本科收治的60例3-4期压力性损伤患者按随机数字表法分成对照组和观察组,每组各30例。对照组给予常规NPWT联合PRP治疗+基础护理;观察组在对照组基础上采取根据本研究建立的标准护理路径进行干预。统计两组患者的创面愈合相关指标、并发症的发生情况及患者满意度情况。结果 观察组的创面愈合率为(89.25±6.32)%,显著优于对照组的(65.18±8.45)%(P<0.001)。观察组创面完全愈合时间(28.56±5.12)d与肉芽组织开始生长时间(4.12±1.05)d均短于对照组(P<0.001)。观察组并发症总发生率为6.67%,低于对照组的26.67%(P=0.038)。观察组患者满意度达96.67%,亦高于对照组的73.33%(P=0.011)。结论 本研究建立的NPWT联合PRP标准化护理路径,可以有效提高3~4期压力性损伤创面愈合质量,减少并发症发生率,提高患者满意度,临床应用价值高且值得推广。

关键词: 压力性损伤;NPWT;PRP;标准化护理路径;创面愈合;并发症

Abstract

Objective To establish a standardized clinical pathway combining negative pressure wound therapy (NPWT) with platelet-rich plasma (PRP) for treating stage 3–4 pressure injuries, investigate its impact on wound healing quality, and provide evidence for standardized clinical nursing practices.
Methods Sixty patients with stage 3–4 pressure injuries admitted to our hospital from January to December 2024 were randomly assigned to an observation group (n=30) and a control group (n=30). The control group received conventional NPWT combined with PRP therapy plus basic nursing care, while the observation group underwent intervention using the established standardized clinical pathway. Wound healing-related indicators, complication rates, and patient satisfaction were compared between groups.
Results The wound healing rate in the observation group (89.25 ± 6.32)% was significantly higher than that in the control group (65.18 ± 8.45)%. The time to complete wound healing (28.56 ± 5.12) days and the time to initial granulation tissue formation (4.12 ± 1.05) days were significantly shorter in the observation group compared to the control group (P < 0.001). The overall complication rate in the observation group (6.67%) was significantly lower than that in the control group (26.67%) (P=0.038). Patient satisfaction in the observation group (96.67%) was significantly higher than that in the control group (73.33%) (P=0.011).
Conclusion   The established NPWT combined with PRP specialized nursing clinical pathway significantly improves the healing quality of Stage 3-4 pressure injuries, reduces complication rates, and enhances patient satisfaction. It demonstrates strong clinical utility and feasibility, warranting widespread adoption.

Key words: Pressure injury; Negative pressure wound therapy; Platelet-rich plasma; Specialized nursing clinical pathway; Wound healing quality; Complications

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引用本文

庞珏, 黄倩倩, 唐欣, 鄢春宁, NPWT联合PRP治疗的标准化护理方案在创面愈合中的应用与效果评价[J]. 国际护理学研究, 2026; 8: (4) : 31-34.