Characteristics and preventive measures of nosocomial infection in patients with gastroenterology
消化内科胃食管反流病的临床治疗方法

摘要

目的 对消化内科胃食管反流病的治疗方法及效果进行研究，以期能够为消化内科医护人员开展后续工作提供些许参考。方法：本次实验共计抽取2018年2月-2020年2月期间就诊的消化内科胃食管反流病患者138例，根据治疗方法的不同将所选患者分为甲组及乙组，两组患者人数相同，各有69人。医护人员在实验过程中通过雷尼替丁对甲组患者进行治疗，通过雷尼替丁及奥美拉唑对乙组患者进行治疗，记录和对比两组胃食管反流病患者不良反应出现情况、症状消失时间及治疗总有效率。结果：研究结果显示，在不良反应出现情况方面，甲组患者共有4例患者出现不良反应，不良反应出现几率为5.80%，乙组患者共有5例患者出现不良反应，不良反应出现几率为7.25%，甲乙两组患者之间差异可以忽略不计，数据并没有表现出统计学意义（p＞0.05）；在症状消失时间方面，乙组远远明显短于甲组患者，甲组患者症状消失时间为（11.5±1.4）天，乙组患者症状消失时间为（6.8±0.8）天，症状消失时间方面表现出较大差异，数据呈现统计学意义（p＜0.05）；在治疗总有效率方面，乙组患者显著高于甲组患者，甲组患者治疗总有效率为82.61%，乙组患者治疗总有效率为94.20%，治疗总有效率方面表现出较大差异，数据呈现统计学意义（p＜0.05）。结论：在消化内科胃食管反流病患者治疗中，相比单一利用雷尼替丁，同时利用雷尼替丁及奥美拉唑的效果更好，能够在一定程度上促进治疗总有效率的提升，具有较强的现实意义。

Abstract

Objective To study the treatment methods and effects of gastroesophageal reflux disease in gastroenterology, in order to provide some reference for the follow-up work of medical staff in gastroenterology.
Methods: In this experiment, a total of 138 patients with gastroesophageal reflux disease from February 2018 to February 2020 were selected. The selected patients were divided into group A and group B according to different treatment methods. The number is the same, with 69 people each. Medical staff treated group A patients with ranitidine during the experiment, and group B patients with ranitidine and omeprazole, recorded and compared the occurrence of adverse reactions in two groups of patients with gastroesophageal reflux disease . The time when symptoms disappear and the total treatment efficiency.
Results: The results of the study showed that in terms of the occurrence of adverse reactions, a total of 4 patients in Group A had adverse reactions, the probability of adverse reactions was 5.80%, and a total of 5 patients in Group B had adverse reactions, and the probability of adverse reactions was 7.25%. The difference between the two groups of patients was negligible, and the data did not show statistical significance (p> 0.05); in terms of the time of symptom disappearance, group B was significantly shorter than the patients in group A. The time for symptoms in group A was (11.5 ± 1.4) days, the time of symptom disappearance in group B patients was (6.8 ± 0.8) days, and there was a large difference in the time of symptom disappearance. The data showed statistical significance (p <0.05); in terms of the total effective rate of treatment, B The patients in group A were significantly higher than those in group A. The total effective rate of treatment in group A was 82.61%, and the total effective rate of treatment in group B was 94.20%. The total effective rate of treatment showed a large difference, and the data showed statistical significance (p < 0.05).
Conclusion  : In the treatment of patients with gastroesophageal reflux disease in gastroenterology, the effect of using ranitidine and omeprazole at the same time is better than that of ranitidine alone, and it can promote the total effective treatment to a certain extent. Ascension has strong practical significance.