The relationship between excessive androgen and abnormal glucose tolerance in patients with polycystic ovary syndrome
多囊卵巢综合征患者雄激素过多与异常糖耐量的关系

摘要

目的 探究多囊卵巢综合征（PCOS）患者雄激素过多与异常糖耐量的关系。方法 于我院选取331例PCOS患者作为实验研究对象，经临床研究调查，确认患者符合PCOS诊断标准，同时，为探讨PCOS患者体内雄激素水平以及与异常糖耐量之间的关系，在其入组后便进行雄激素和异常糖耐量的检验试验。结果 经调查分析来看，组内331例患者中，共出现29例异常糖耐量患者，其中BMI指数≥23kg/m2的异常糖耐量发生率更高；同时，不同葡萄糖代谢状态的PCOS患者，其雄激素水平也有着较大的差异，尤其是糖耐量正常与糖尿病前期、2型糖尿病患者相比。结论 PCOS患者的糖耐量异常发生率与多方面因素有关，其中雄激素水平过高及肥胖是主要影响因素，对此应加强对PCOS患者的早期干预，降低后期风险发生率。

Abstract

Objective: To explore the relationship between androgen excess and abnormal glucose tolerance in patients with polycystic ovary syndrome (PCOS).
Methods: In our hospital, 331 patients with PCOS were selected as experimental research objects. After clinical research investigations, it was confirmed that the patients met the diagnostic criteria of PCOS. At the same time, in order to explore the relationship between androgen levels in PCOS patients and the relationship between abnormal glucose tolerance, in their entry After the group, androgen and abnormal glucose tolerance test were performed.
Results: According to the investigation and analysis, among the 331 patients in the group, 29 patients with abnormal glucose tolerance occurred. Among them, the incidence of abnormal glucose tolerance with BMI index ≥23kg/m2 was higher; at the same time, PCOS patients with different glucose metabolism status, There are also big differences in androgen levels, especially in patients with normal glucose tolerance compared with prediabetes and type 2 diabetes.
Conclusion  : The incidence of impaired glucose tolerance in PCOS patients is related to many factors, among which high androgen levels and obesity are the main influencing factors. For this, early intervention in PCOS patients should be strengthened to reduce the incidence of later risk.