Retrospective analysis of the observation and nursing points of continuous renal replacement therapy in the treatment of severe acute renal failure
回顾分析连续性肾脏替代疗法在救治重症急性肾功能衰竭中的观察和护理要点

摘要

目的 探究回顾分析连续性肾脏替代疗法（CRRT）在救治重症急性肾功能衰竭（ARF）中的观察和护理要点。方法 将2020年8月～2021年9月在本院行CRRT治疗的ARF患者90例随机分为参照组（间歇性血液透析治疗）与研究组（ARF治疗），各45例。对比2组白细胞介素-6（IL-6）、白细胞介素-8（IL-8）、超敏C反应蛋白（hs-CRP）、肿瘤坏死因子-a（TNF-a）等炎症因子水平及血清肌酐（SCr）、内生肌酐清除率（Ccr）、尿素氮（BUN）、胆碱酯酶（CHE）等肾功能指标与治疗效果及并发症发生情况，并总结护理要点。结果 研究组治疗有效率95.56%高于参照组77.78%（P<0.05）；研究组IL-6、IL-8、hs-CRP、TNF-α均低于参照组（P<0.05）；研究组SCr、Ccr、BUN、CHE水平均优于参照组（P<0.05）；研究组并发症发生率4.44%低于参照组22.22%（P<0.05）。结论 CRRT可降低炎症因子水平与并发症发生率，改善肾功能，提高治疗效果。

Abstract

Objective To explore and retrospectively analyze the observation and nursing points of continuous renal replacement therapy (CRRT) in the treatment of severe acute renal failure (ARF).
Methods 90 patients with ARF who underwent CRRT in our hospital from August 2020 to September 2021 were randomly divided into reference group (intermittent hemodialysis treatment) and study group (ARF treatment), with 45 cases in each group. The levels of inflammatory factors such as interleukin-6 (IL-6), interleukin-8 (IL-8), high-sensitivity C-reactive protein (hs CRP), tumor necrosis factor-A (TNF-a), renal function indexes such as serum creatinine (SCR), endogenous creatinine clearance (CCR), urea nitrogen (BUN), cholinesterase (CHE), treatment effect and complications were compared between the two groups, and the key points of nursing were summarized.
Results the effective rate of the study group was 95.56% higher than 77.78% in the reference group (P < 0.05); Study group IL-6, IL-8, hs CRP, TNF- α All were lower than those in the reference group (P < 0.05); The levels of SCR, CCR, bun and ChE in the study group were better than those in the reference group (P < 0.05); The incidence of complications in the study group was 4.44%, which was lower than 22.22% in the reference group (P < 0.05).
Conclusion   CRRT can reduce the level of inflammatory factors and the incidence of complications, improve renal function and improve the therapeutic effect.